Categoria: Artigos
-
16 ago 2020
>> Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomized, double-blind, controlled, parallel-group, phase 2b trial
-
Título do Estudo Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomized, double-blind, controlled, parallel-group, phase 2b trial Fonte Lancet Resp Med, publicado online em 25/02/2020 https://doi.org/10.1016/S2213-2600(19)30471-01. Introdução Tosse por mais de 8 semanas afeta 4 a 10% de adultos no mundo. Embora muitos pacientes se […]
-
8 ago 2020
>> Relationship between Symptoms, Exacerbations, and Treatment Response in Bronchiectasis
-
Título do Estudo Relationship between Symptoms, Exacerbations, and Treatment Response in Bronchiectasis Fonte American Journal of Respiratory and Critical Care Medicine. 1461-1462. 15 Jun-2020 Desenho do Estudo Estudo de coorte observacional com 333 pacientes do leste da Escócia (2012-2016). Os sintomas foram modelados como uma variável contínua e os pacientes foram classificados em 3 […]
-
1 ago 2020
>> Invasive staging procedures do not prevent nodal metastases from being missed in stage I lung cancer
-
Título do Estudo Invasive staging procedures do not prevent nodal metastases from being missed in stage I lung cancer Fonte (Ann Thorac Surg 2020;-:—) – 2020 by The Society of Thoracic Surgeons – [https://doi.org/10.1016/j.athoracsur.2020.03.026] Objetivos Determinar até que ponto o estadiamento invasivo do mediastino por EBUS, mediastinoscopia ou ambos em associação aos métodos de imagem […]
-
25 jul 2020
>> Short-term and long-term effect of a high-intensity pulmonary rehabilitation programme in obese patients with asthma: a randomised controlled trial
-
Título do Estudo Short-term and long-term effect of a high-intensity pulmonary rehabilitation programme in obese patients with asthma: a randomised controlled trial Fonte European Respiratory Journal 56 (1) 1901820; DOI: 10.1183/13993003.01820-2019 Published 2 July 2020. Objetivos Determinar os efeitos a curto e longo prazo de um programa de reabilitação pulmonar (RP) de alta […]
-
18 jul 2020
>> Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis
-
Título do Estudo Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis Fonte European Respiratory Journal 2020 55: 1902150. Objetivos Altos níveis da fração de óxido nítrico exalado (FENO) estão associados a um maior risco de exacerbação da asma. No entanto, […]
-
11 jul 2020
>> b-Blockers in COPD A Cohort Study From the TONADO Research Program
-
Título do Estudo b-Blockers in COPD A Cohort Study From the TONADO Research Program Fonte CHEST 2018; 153(6):1315-1325. Desenho do Estudo Os grandes estudos (5.162 doentes) fase III TONADO 1 e 2 avaliaram os desfechos relatados pelo paciente em pacientes com DPOC moderada a muito grave (GOLD2-4)recebendo tratamento broncodilatador (Olodaterol/Tiotrópio) de ação prolongada […]
-
4 jul 2020
>> A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19
-
Título do Estudo A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19 Fonte The New England Journal of Medicine. June 3, 2020. Desenho do Estudo Estudo randomizado, duplo-cego, controlado por placebo, em todo os Estados Unidos e partes do Canadá testando a hidroxicloroquina como produto pós-exposição como profilaxia a Covid19. Foram incluídos adultos que […]
-
27 jun 2020
>> Survey of Insomnia and Related Social Psychological Factors Among Medical Staff Involved in the 2019 Novel Coronavirus Disease Outbreak
-
Título do Estudo Survey of Insomnia and Related Social Psychological Factors Among Medical Staff Involved in the 2019 Novel Coronavirus Disease Outbreak Fonte Zhang C, Yang L, Liu S, et al. Survey of Insomnia and Related Social Psychological Factors Among Medical Staff Involved in the 2019 Novel Coronavirus Disease Outbreak. Front Psychiatry. 2020;11:306. Published 2020 […]
-
20 jun 2020
>> Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study
-
Título do Estudo Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study Fonte Cummings MJ, Baldwin MR, Abrams D, et al. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet. 2020;395(10239):1763-1770. doi:10.1016/S0140-6736(20)31189-2. Desenho […]
-
13 jun 2020
>> Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
-
Título do Estudo Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 Fonte Lai J, Ma S, Wang Y, et al. Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019. JAMA Netw Open. 2020;3(3):e203976. doi:10.1001/jamanetworkopen.2020.3976. Desenho do Estudo 1- Objetivo: avaliar fatores […]