Categoria: Artigos
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28 nov 2020
>> Risk reduction and right heart reverse remodeling by upfront triple combination therapy in pulmonary arterial hypertension
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Título do Estudo Risk reduction and right heart reverse remodeling by upfront triple combination therapy in pulmonary arterial hypertension Fonte D’Alto M, Badagliacca R, Argiento P, et al. Risk Reduction and Right Heart Reverse Remodeling by Upfront Triple Combination Therapy in Pulmonary Arterial Hypertension. Chest. 2020;157(2):376-383. doi: 10.1016/j.chest.2019.09.009. Desenho do Estudo 1- Objetivo: […]
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21 nov 2020
>> Preventive tuberculosis treatment effect on QuantiFERON TB-Gold in-tube testing in a high tuberculosis-endemic country: A clinical trial
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Título do Estudo Preventive tuberculosis treatment effect on QuantiFERON TB-Gold in-tube testing in a high tuberculosis-endemic country: A clinical trial Fonte Q. Yang et al. / International Journal of Infectious Diseases 91 (2020) 182–187 – Preventive tuberculosis treatment effect on QuantiFERON TB-Gold in-tube testing in a high tuberculosis-endemic country: A clinical trial – DOI […]
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14 nov 2020
>> COVID-19, Sistema Renina-Angiotensina, Enzima Conversora da Angiotensina 2 e Nicotina: Qual a Inter-Relação?
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Título do Estudo COVID-19, Sistema Renina-Angiotensina, Enzima Conversora da Angiotensina 2 e Nicotina: Qual a Inter-Relação? Fonte JR Scholz, MACQ Lopes, JFK Saraiva, FC Colombo – Arq Bras Cardiol. 2020; 115(4):708-711 – DOI: https://doi.org/10.36660/abc.20200653 Resumo do Estudo O Sistema Renina-Angiotensina (SRA) é classicamente importante regulador da homeostase eletrolítica e da pressão arterial. Mais recentemente […]
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7 nov 2020
>> Continuous positive airway pressure versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): a multicentre, randomised controlled trial
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Título do Estudo Continuous positive airway pressure versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): a multicentre, randomised controlled trial Fonte Lancet Respir Med 2020 Apr;8(4):349-358. doi: 10.1016/S2213-2600(19)30402-3. Epub 2019 Dec 2.. Desenho do Estudo Estudo multicêntrico (11 centros de sono do Reino Unido), randomizado, comparando o efeito do […]
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31 out 2020
>> Real World Effectiveness of Benralizumab in Severe Eosinophilic Asthma
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Título do Estudo Real World Effectiveness of Benralizumab in Severe Eosinophilic Asthma Fonte Kavanagh JE, Hearn AP, Dhariwal J, Gráinne d’Ancona, Douiri A, Roxas C, Fernandes M, Green L, Thomson L, Nanzer AM, Kent BD, Jackson DJ. Real World Effectiveness of Benralizumab in Severe Eosinophilic Asthma. Chest. 2020 Aug 31:S0012-3692(20)34313-0. doi: 10.1016/j.chest.2020.08.2083. Epub ahead […]
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24 out 2020
>> Progressive interstitial lung disease in patients with systemic sclerosis-associated interstitial lung disease in the EUSTAR database
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Título do Estudo Progressive interstitial lung disease in patients with systemic sclerosis-associated interstitial lung disease in the EUSTAR database Fonte Hoffmann-Vold A, Allanore Y, Alves M, et al. Progressive interstitial lung disease in patients with systemic sclerosis-associated interstitial lung disease in the EUSTAR database. Annals of the Rheumatic Diseases Published Online First: 28 September 2020. doi: 10.1136/annrheumdis-2020-217455. Introdução A esclerose sistêmica é […]
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17 out 2020
>> Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer
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Título do Estudo Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer Fonte Wu YL, Tsuboi M., He J et al. Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer. N Engl J Med 2020; epub ahead of printing. DOI: 10.1056/NEJMoa2027071. Desenho do Estudo 1- Objetivo: avaliar a eficácia do uso de osimertinibe, inibidor de EGFR de […]
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10 out 2020
>> COVID-19 and multisystem inflammatory syndrome in children and adolescents
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Título do Estudo COVID-19 and multisystem inflammatory syndrome in children and adolescents Fonte Li Jiang, Kun Tang, Mike Levin, et al. COVID-19 and multisystem inflammatory syndrome in children and adolescents. www.thelancet.com/infection Published on line August1, 2020. https://doi.org/10.1016/S1473-3099(20)30651-4. Desenho do Estudo Os autores revisaram a epidemiologia, as possíveis causas, as características clínicas e os […]
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4 out 2020
>> Caring for patients with COPD and COVID-19: a viewpoint to spark discussion
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Título do Estudo Caring for patients with COPD and COVID-19: a viewpoint to spark discussion Fonte Sami O Simons , John R Hurst ,2 Marc Miravitlles, Frits M E Franssen,1,4 Daisy J A Janssen ,4,5 Alberto Papi,6 Marieke L Duiverman ,7,8 Huib A M Kerstjens8,9 Introdução Trata-se de um artigo misto de […]
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26 set 2020
>> Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial
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Título do Estudo Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial Fonte Lancet Respir Med 2020; in press (https://doi.org/10.1016/ S2213-2600(20)30398-2). Objetivos Avaliar a eficácia e segurança do uso de terapia tripla fechada em pacientes com asma não […]